Coronavirus Drug Finally Found

Coronavirus Drug Finally Found

UK researchers has announced that low-dose steroid treatment dexamethasone is the major breakthrough in the fight against the deadly virus called COVID-19.

In the trial, led by a team from Oxford University, around 2,000 hospital patients were given dexamethasone and were compared with more than 4,000 who did not receive the drug.

For patients on ventilators, it cuts the risk of death from 40% to 28%. For patients needing oxygen, it cuts the risk of death from 25% to 20%.

Chief investigator, Prof. Peter Horby said: “This is the only drug so far that has been shown to reduce mortality – and it reduces it significantly. It’s a major breakthrough

Lead researcher, Prof. Martin Landray says the findings suggest that for every eight patients treated on ventilators, you could save one life.

For those patients treated with oxygen, you save one life for approximately every 20-25 treated with the drug.

“There is a clear, clear benefit. The treatment is up to 10 days of dexamethasone and it costs about £5 per patient. So, essentially, it costs £35 to save a life. This is a drug that is globally available.”

Prof Landray said, when appropriate hospital patients should now be given  without delay, but people should not go out and buy it to take at home.

Dexamethasone does not appear to help people with milder symptoms of coronavirus – those who don’t need help with their breathing.

The Recovery Trial has been running since March. It included the malaria drug hydroxychloroquine which has subsequently been ditched amid concerns that it increases fatalities and heart problems.

Also, a drug called remdesivir, an antiviral treatment that appears to shorten recovery time for people with coronavirus, is already being made available on the NHS.

It also disclosed that its part of the world’s biggest trial testing existing treatments to see if they also work for coronavirus.

"It cuts the risk of death by a third for patients on ventilators. For those on oxygen, it cut deaths by a fifth."

According to the researchers, the drug had been used to treat patients in the UK from the start of the pandemic, up to 5,000 lives could have been saved and could be of huge benefit in poorer countries with high numbers of Covid-19 patients.

About 19 out of 20 patients with coronavirus recovered without being admitted to hospital. Of those who were admitted to hospital, most also recovered, but some may need oxygen or mechanical ventilation. These are the high-risk patients whom dexamethasone appears to help.

The drug is already used to reduce inflammation in a range of other conditions, and it appears that it helps stop some of the damage that can happen when the body’s immune system goes into overdrive as it tries to fight off coronavirus.

The body’s over-reaction is called a cytokine storm and it can be deadly.

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